Epistasis describes a condition whereby one gene controls the expression of another gene
In mice, the expression of a specific fur colour by one gene is dependent upon the production of hair pigment by another gene
- Black fur (B) is dominant to brown fur (b), but in the absence of hair pigment (cc) mice will appear albino
In humans, the gene for baldness supersedes genes for hair colour and hence is epistatic in nature
Epistasis – Mouse Coat Colour
